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Article

Variants of the melanocortin-1 receptor: do they matter clinically?

Experimental dermatology - 1 Jan 2015

Haddadeen Ciara, Lai Chester, Cho Shin-Young, Healy Eugene

Abstract excerpt

The melanocortin 1 receptor (MC1R) gene encodes for a seven-pass transmembrane receptor primarily expressed on melanocytes and melanoma cells. Single nucleotide polymorphisms (SNPs, also termed variants) in MC1R frequently cause red hair, fair skin and are associated with melanoma and keratinocyt...

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Identifiers

PMID: 25219681
DOI: 10.1111/exd.12540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25219681-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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