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Article

Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility.

Photodermatology, photoimmunology & photomedicine - 1 Dec 2004

Healy Eugene

Abstract excerpt

The melanocortin 1 receptor is a key regulator of variation in normal human pigmentation. Genetic variants of this receptor cause red hair and fair skin, and several case-control studies have demonstrated that these genetic variants increase the risk of skin cancer development in humans. The mechanism whereby the risks of skin cancer are increased is not entirely clear, and may be because of a combination of...

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Identifiers

PMID: 15533235
DOI: 10.1111/j.1600-0781.2004.00132.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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