Article
Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility.
Photodermatology, photoimmunology & photomedicine - 1 Dec 2004
Healy Eugene
Abstract excerpt
The melanocortin 1 receptor is a key regulator of variation in normal human pigmentation. Genetic variants of this receptor cause red hair and fair skin, and several case-control studies have demonstrated that these genetic variants increase the risk of skin cancer development in humans. The mech...
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