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Article

The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI.

Translational psychiatry - 3 Jul 2012

Whalley H C, Papmeyer M, Sprooten E, Romaniuk L, Blackwood D H, Glahn D C, Hall J, Lawrie S M, Sussmann Je, McIntosh A M

Abstract excerpt

Genome-wide association studies (GWAS) have demonstrated a significant polygenic contribution to bipolar disorder (BD) where disease risk is determined by the summation of many alleles of small individual magnitude. Modelling polygenic risk scores may be a powerful way of identifying disrupted br...

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PMID: 22760554
DOI: 10.1038/tp.2012.60
PMCID: PMC3410628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22760554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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