Article
Neurocognitive correlates of polygenic risk for bipolar disorder among youth with and without bipolar disorder.
Journal of affective disorders - 15 Jan 2025
Jiang Xinyue, Zai Clement, Mio Megan, Dimick Mikaela K, Sultan Alysha A, Young L Trevor, Goldstein Benjamin I
Abstract excerpt
INTRODUCTION: There is well-established evidence of reduced neurocognitive performance in adults and youth with bipolar disorder (BD). However, little is known about the polygenic underpinnings of neurocognition in individuals with BD, particularly in youth. The current study aimed to examine the association between polygenic risk score for BD (BD-PRS) and neurocognition among youth with BD and healthy controls...
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