Article
Using structural MRI to identify individuals at genetic risk for bipolar disorders: a 2-cohort, machine learning study.
Journal of psychiatry & neuroscience : JPN - 1 Sept 2015
Hajek Tomas, Cooke Christopher, Kopecek Miloslav, Novak Tomas, Hoschl Cyril, Alda Martin
Abstract excerpt
BACKGROUND: Brain imaging is of limited diagnostic use in psychiatry owing to clinical heterogeneity and low sensitivity/specificity of between-group neuroimaging differences. Machine learning (ML) may better translate neuroimaging to the level of individual participants. Studying unaffected offspring of parents with bipolar disorders (BD) decreases clinical heterogeneity and thus increases sensitivity for...
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