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Article

Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder.

PloS one - 1 Jan 2015

Tesli Martin, Kauppi Karolina, Bettella Francesco, Brandt Christine Lycke, Kaufmann Tobias, Espeseth Thomas, Mattingsdal Morten, Agartz Ingrid, Melle Ingrid, Djurovic Srdjan, Westlye Lars T, Andreassen Ole A

Abstract excerpt

OBJECTIVES: Bipolar disorder (BD) is a highly heritable disorder with polygenic inheritance. Among the most consistent findings from functional magnetic imaging (fMRI) studies are limbic hyperactivation and dorsal hypoactivation. However, the relation between reported brain functional abnormalities and underlying genetic risk remains elusive. This is the first cross-sectional study applying a whole-brain...

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Identifiers

PMID: 26222050
DOI: 10.1371/journal.pone.0134202
PMCID: PMC4519303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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