Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex.

doi:10.1002/hbm.25667

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Article

Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex.

Human brain mapping - 15 Dec 2021

Takeuchi Hikaru, Kimura Ryosuke, Tomita Hiroaki, Taki Yasuyuki, Kikuchi Yoshie, Ono Chiaki, Yu Zhiqian, Matsudaira Izumi, Nouchi Rui, Yokoyama Ryoichi, Kotozaki Yuka, Nakagawa Seishu, Hanawa Sugiko, Iizuka Kunio, Sekiguchi Atsushi, Araki Tsuyoshi, Miyauchi Carlos Makoto, Ikeda Shigeyuki, Sakaki Kohei, Dos S Kawata Kelssy H, Nozawa Takayuki, Yokota Susumu, Magistro Daniele, Imanishi Tadashi, Kawashima Ryuta

Abstract excerpt

It has been hypothesized that a higher genetic risk of bipolar disorder (BD) is associated with greater creativity. Given the clinical importance of bipolar disorder and the importance of creativity to human society and cultural development, it is essential to reveal their associations and the neural basis of the genetic risk of bipolar disorder to gain insight into its etiology. However, despite the previous...

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PMID: 34587347
DOI: 10.1002/hbm.25667
PMCID: PMC8596941

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