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Article

Domain landscapes of somatic mutations in cancer.

BMC genomics - 18 Jun 2012

Nehrt Nathan L, Peterson Thomas A, Park DoHwan, Kann Maricel G

Abstract excerpt

BACKGROUND: Large-scale tumor sequencing projects are now underway to identify genetic mutations that drive tumor initiation and development. Most studies take a gene-based approach to identifying driver mutations, highlighting genes mutated in a large percentage of tumor samples as those likely...

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Identifiers

PMID: 22759657
DOI: 10.1186/1471-2164-13-S4-S9
PMCID: PMC3394412

Genes

APC
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22759657-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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