Article
Cancer genome landscapes.
Science (New York, N.Y.) - 29 Mar 2013
Vogelstein Bert, Papadopoulos Nickolas, Velculescu Victor E, Zhou Shibin, Diaz Luis A, Kinzler Kenneth W
Abstract excerpt
Over the past decade, comprehensive sequencing efforts have revealed the genomic landscapes of common forms of human cancer. For most cancer types, this landscape consists of a small number of "mountains" (genes altered in a high percentage of tumors) and a much larger number of "hills" (genes altered infrequently). To date, these studies have revealed ~140 genes that, when altered by intragenic mutations, can...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.