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Article

Co-expressions of casein kinase 2 (CK2) subunits restore the down-regulation of tubulin levels and disruption of microtubule structures caused by PrP mutants.

Journal of molecular neuroscience : MN - 1 May 2013

Wang Zhao-Yun, Shi Qi, Wang Shao-Bin, Tian Chan, Xu Ying, Guo Yan, Chen Cao, Zhang Jin, Dong Xiao-Ping

Abstract excerpt

CK2 shows disease-associated alteration in the scrapie experimental rodents and human prion diseases. In this study, mammalian expressing plasmids for human CK2 subunits, CK2α and CK2β, were generated. Immunoprecipitation assays revealed stronger signals of PrP-CK2α complexes in the HEK293 cells co-transfected with plasmids expressing CK2α and various PrP constructs, including PG5, CytoPrP, PG9, and PG12....

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Identifiers

PMID: 22752506
DOI: 10.1007/s12031-012-9845-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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