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Cellular Prion Protein Role in Cancer Biology: Is It A Potential Therapeutic Target?

7 Nov 2022

Abstract excerpt

Cancers are worldwide health concerns, whether they are sporadic or hereditary. The fundamental mechanism that causes somatic or oncogenic mutations and ultimately aids cancer development is still unknown. However, mammalian cells with protein-only somatic inheritance may also contribute to cancerous malignancies. Emerging data from a recent study show that prion-like proteins and prions (PrPC) are crucial...

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PMID: 36359353
DOI: 10.3390/biomedicines10112833

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