Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging roles of the cellular prion protein (PrPC) and 37/67 kDa laminin receptor (RPSA) interaction in cancer biology

15 Jul 2023

Abstract excerpt

Abstract The cellular prion protein (PrPC) is well-known for its involvement, under its pathogenic protease-resistant form (PrPSc), in a group of neurodegenerative diseases, known as prion diseases. PrPC is expressed in nervous system, as well as in other peripheral organs, and has been found overexpressed in several types of solid tumors. Notwithstanding, studies in recent years have disclosed an emerging role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Prion Diseases and Protein Misfolding
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37452879
DOI: 10.1007/s00018-023-04844-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging roles of the cellular prion protein (PrPC) and 37/67 kDa laminin receptor (RPSA) interaction in cancer biologyPMID 37452879Read ↗

Interactions between PrPc and other ligands with the 37-kDa/67-kDa laminin receptorSemantic proximity Read ↗

Cellular Prion Protein Role in Cancer Biology: Is It A Potential Therapeutic Target?Semantic proximity Read ↗

The Cellular Prion Protein and the Hallmarks of CancerSemantic proximity Read ↗

Looking into laminin receptor: critical discussion regarding the non‐integrin 37/67‐<scp>kDa</scp>laminin receptor/<scp>RPSA</scp>proteinSemantic proximity Read ↗

LRP/LR as an alternative promising target in therapy of prion diseases, Alzheimer's disease and cancer.Semantic proximity Read ↗

Cellular prion protein (PrPC) in the development of Merlin-deficient tumours.Semantic proximity Read ↗

A trans-dominant negative 37kDa/67kDa laminin receptor mutant impairs PrP(Sc) propagation in scrapie-infected neuronal cells.Semantic proximity Read ↗

Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1.Semantic proximity Read ↗

The multiple functions of PrPC in physiological, cancer, and neurodegenerative contextsSemantic proximity Read ↗

PRNP is a pan-cancer prognostic and immunity-related to EMT in colorectal cancerSemantic proximity Read ↗

PrPC-Neutralizing Antibody Confers an Additive Benefit in Combination with 5-Fluorouracil in KRAS-Mutant Colorectal Cancer Models, Associated with Reduced RAS-GTP and AKT/ERK Phosphorylation.Semantic proximity Read ↗

Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.