Article

Protein kinase CK2α’ as a dual modulator of immune signaling and synaptic dysfunction in Tauopathy

2025-06-25

Abstract excerpt

Tauopathies are a group of neurodegenerative diseases characterized by tau accumulation, neuroinflammation, and synaptic dysfunction, yet effective treatments remain elusive. Protein Kinase CK2 has been previously associated with different aspects of tau pathology but genetic evidence for the contribution of CK2 to tauopathy remained lacking. Here, we show CK2α’, one of the two catalytic subunits of CK2, as a nove...

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Identifiers and source

Literature Corpus work: 07ca3cb8-b1d9-5ab7-8aa2-8d53a91d4255
DOI: 10.1101/2025.06.24.661391

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