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Article

Protein Kinase CK2 and Its Potential Role as a Therapeutic Target in Huntington’s Disease

15 Aug 2022

Abstract excerpt

gene, for which no disease modifying therapies are currently available. Much of the recent research has focused on developing therapies to directly lower HTT expression, and while promising, these therapies have presented several challenges regarding administration and efficacy. Another promising therapeutic approach is the modulation of HTT post-translational modifications (PTMs) that are dysregulated in disease...

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PMID: 36009526
DOI: 10.3390/biomedicines10081979

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