Article
The production of soluble C-type lectin-like receptor 2 is a regulated process.
Glycoconjugate journal - 1 Aug 2012
Fei Min, Zhou Lei, Xie Jianhui, Ruan Yuanyuan, Xu Jiejie, He Songbin, Shen Hongjie, Hu Yumin, Ren Shifang, Ruan Changgeng
Abstract excerpt
C-type lectin-like receptor 2 (CLEC-2) is a newly identified type II transmembrane protein belonging to the C-type lectin family molecules, which acts as a cell-surface receptor for snake venom toxin rhodocytin and tumor antigen podoplanin. We previously demonstrated that the full-length mouse CLEC-2 (mCLEC-2) can be cleaved into soluble form. Elevated levels of soluble forms of membrane proteins in circulating...
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