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Article

The human complement fragment receptor, C5L2, is a recycling decoy receptor.

Molecular immunology - 1 Mar 2009

Scola Anne-Marie, Johswich Kay-Ole, Morgan B Paul, Klos Andreas, Monk Peter N

Abstract excerpt

C5L2 is a 7 transmembrane domain receptor for complement fragment C5a that, unlike the classical C5a receptor, C5aR, does not couple to G proteins. However, in mice where C5L2 has been deleted, the response to C5a is altered, suggesting that C5L2 may have a signaling function. In order to investigate whether human C5L2 also has some capacity to transduce signals, we have attempted to produce a signaling competent...

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Identifiers

PMID: 19100624
DOI: 10.1016/j.molimm.2008.11.001
PMCID: PMC2697321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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