Article
PIP₂ modulation of Slick and Slack K⁺ channels.
Biochemical and biophysical research communications - 27 Jul 2012
de los Angeles Tejada Maria, Jensen Lars Jørn, Klaerke Dan A
Abstract excerpt
Slick and Slack are members of the Slo family of high-conductance potassium channels. These channels are activated by Na(+) and Cl(-) and are highly expressed in the CNS, where they are believed to contribute to the resting membrane potential of neurons and the control of excitability. Herein, we provide evidence that Slick and Slack channels are regulated by the phosphoinositide PIP(2). Two stereoisomers of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.