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Article

Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies.

Neuron - 13 Jun 2002

Lopes Coeli M B, Zhang Hailin, Rohacs Tibor, Jin Taihao, Yang Jian, Logothetis Diomedes E

Abstract excerpt

Inwardly rectifying K(+) (Kir) channels are important regulators of resting membrane potential and cell excitability. The activity of Kir channels is critically dependent on the integrity of channel interactions with phosphatidylinositol 4,5-bisphosphate (PIP(2)). Here we identify and characteriz...

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Source

Identifiers

PMID: 12086641
DOI: 10.1016/s0896-6273(02)00725-0

Genes

PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12086641-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies.PMID 12086641Read ↗

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