Article
The sodium-activated potassium channel is encoded by a member of the Slo gene family.
Neuron - 6 Mar 2003
Yuan Alex, Santi Celia M, Wei Aguan, Wang Zhao Wen, Pollak Kelly, Nonet Michael, Kaczmarek Leonard, Crowder C Michael, Salkoff Lawrence
Abstract excerpt
Na(+)-activated potassium channels (K(Na)) have been identified in cardiomyocytes and neurons where they may provide protection against ischemia. We now report that K(Na) is encoded by the rSlo2 gene (also called Slack), the mammalian ortholog of slo-2 in C. elegans. rSlo2, heterologously expressed, shares many properties of native K(Na) including activation by intracellular Na(+), high conductance, and prominent...
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