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Article

Genome-wide somatic copy number alterations in low-grade PanINs and IPMNs from individuals with a family history of pancreatic cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2012

Hong Seung-Mo, Vincent Audrey, Kanda Mitsuro, Leclerc Julie, Omura Noriyuki, Borges Michael, Klein Alison P, Canto Marcia Irene, Hruban Ralph H, Goggins Michael

Abstract excerpt

PURPOSE: Characterizing the earliest chromosomal alterations of pancreatic precursor neoplasms from individuals with a familial aggregation of pancreatic cancer may provide clues as to the loci of pancreatic cancer susceptibility genes. EXPERIMENTAL DESIGN: We used Illumina 370/660K SNP arrays to conduct genome-wide copy number analysis in 60 benign neoplasms [58 mostly low-grade pancreatic intraepithelial...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22723370
DOI: 10.1158/1078-0432.CCR-12-1075
PMCID: PMC3629843

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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