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Article

Genomic Characterization of Low- and High-Grade Pancreatic Mucinous Cystic Neoplasms Reveals Recurrent KRAS Alterations in "High-Risk" Lesions.

Pancreas - 1 Jan 2000

Conner James R, Mariño-Enríquez Adrián, Mino-Kenudson Mari, Garcia Elizabeth, Pitman Martha B, Sholl Lynette M, Srivastava Amitabh, Doyle Leona A

Abstract excerpt

OBJECTIVES: Pancreatic ductal adenocarcinoma arises from the following 3 distinct precursor lesions: pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and mucinous cystic neoplasm (MCN). Genetic abnormalities in the first 2 precursor lesions have been well characterized, but there are limited data on progression pathways in MCNs. This study aimed to characterize genomic differences...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Grading

Share to Neoplasms, Cystic, Mucinous, and Serous

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Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 28196015
DOI: 10.1097/MPA.0000000000000805

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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