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Article

Genomic landscape of pancreatic neuroendocrine tumors.

World journal of gastroenterology - 14 Dec 2014

Gebauer Niklas, Schmidt-Werthern Christian, Bernard Veronica, Feller Alfred C, Keck Tobias, Begum Nehara, Rades Dirk, Lehnert Hendrik, Brabant Georg, Thorns Christoph

Abstract excerpt

AIM: To investigate the prognostic role of genomic stability and copy number alterations (CNAs) pancreatic neuroendocrine tumors (PanNETs). METHODS: A high-resolution array-based comparative genomic hybridization approach was utilized in order to investigate and quantify chromosomal aberrations in a panel of 37 primary PanNET and 11 metastatic samples. DNA samples were extracted from formalin-fixed and...

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Identifiers

PMID: 25516664
DOI: 10.3748/wjg.v20.i46.17498
PMCID: PMC4265611

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