Article
A novel germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men.
The Prostate - 1 Jan 2013
Lin Xiaoling, Qu Lianxi, Chen Zhuo, Xu Chuanliang, Ye Dingwei, Shao Qiang, Wang Xiang, Qi Jun, Chen Zhiwen, Zhou Fangjian, Wang Meilin, Wang Zhong, He Dalin, Wu Denglong, Gao Xin, Yuan Jianlin, Wang Gongxian, Xu Yong, Wang Guozeng, Dong Pei, Jiao Yang, Yang Jin, Ou-Yang Jun, Jiang Haowen, Zhu Yao, Ren Shancheng, Zhang Zhengdong, Yin Changjun, Wu Qijun, Zheng Ying, Turner Aubrey R, Tao Sha, Na Rong, Ding Qiang, Lu Daru, Shi Rong, Sun Jielin, Liu Fang, Zheng S Lilly, Mo Zengnan, Sun Yinghao, Xu Jianfeng
Abstract excerpt
BACKGROUND: A rare mutation G84E in HOXB13 was recently identified to be associated with prostate cancer (PCa) in Caucasians. The goal of this study is to test association between HOXB13 genetic variants and PCa risk in Chinese men. METHODS: All study subjects were part of the Chinese Consortium for Prostate Cancer Genetics (ChinaPCa). In the first stage, we screened for mutations by sequencing the HOXB13 coding...
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