Article
Random or stochastic monoallelic expressed genes are enriched for neurodevelopmental disorder candidate genes.
PloS one - 1 Jan 2013
Jeffries Aaron R, Collier David A, Vassos Evangelos, Curran Sarah, Ogilvie Caroline M, Price Jack
Abstract excerpt
Random or stochastic monoallelic expressed genes (StMA genes) represent a unique form of monoallelic expression where allelic choice is made at random early in development. The consequential clonal diversity provides opportunity for functional heterozygosity in tissues such as the brain, and can impact on both development and disease. We investigate the relationship of StMA expressed genes previously identified...
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