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Article

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis.

BMC genomics - 10 Nov 2017

Zhao Dejian, Lin Mingyan, Pedrosa Erika, Lachman Herbert M, Zheng Deyou

Abstract excerpt

BACKGROUND: Monoallelic expression of autosomal genes has been implicated in human psychiatric disorders. However, there is a paucity of allelic expression studies in human brain cells at the single cell and genome wide levels. RESULTS: In this report, we reanalyzed a previously published single-cell RNA-seq dataset from several postmortem human brains and observed pervasive monoallelic expression in individual...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29126398
DOI: 10.1186/s12864-017-4261-x
PMCID: PMC5681780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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