Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele-biased expression in differentiating human neurons: implications for neuropsychiatric disorders.

PloS one - 1 Jan 2012

Lin Mingyan, Hrabovsky Anastasia, Pedrosa Erika, Wang Tao, Zheng Deyou, Lachman Herbert M

Abstract excerpt

Stochastic processes and imprinting, along with genetic factors, lead to monoallelic or allele-biased gene expression. Stochastic monoallelic expression fine-tunes information processing in immune cells and the olfactory system, and imprinting plays an important role in development. Recent studies suggest that both stochastic events and imprinting may be more widespread than previously considered. We are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child Development Disorders, Pervasive
Share to Induced Pluripotent Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mental Disorders

Share to Neurogenesis

Share to Neurons

Share to Oligonucleotide Array Sequence Analysis

Share to Schizophrenia

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 22952857
DOI: 10.1371/journal.pone.0044017
PMCID: PMC3431331

Genes

ERBB4
NLGN1
NRG1
NRG3
NRXN1
RBFOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allele-biased expression in differentiating human neurons: implications for neuropsychiatric disorders.PMID 22952857Read ↗

Stochastic choice of allelic expression in human neural stem cells.Semantic proximity Read ↗

Random or stochastic monoallelic expressed genes are enriched for neurodevelopmental disorder candidate genes.Semantic proximity Read ↗

Epigenetic and Cellular Diversity in the Brain through Allele-Specific Effects.Semantic proximity Read ↗

Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis.Semantic proximity Read ↗

Inference of cell-type specific imprinted regulatory elements and genes during human neuronal differentiationSemantic proximity Read ↗

Diverse Patterns of Allele-Specific Expression in Healthy Human TissuesSemantic proximity Read ↗

Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain.Semantic proximity Read ↗

Cell-specific expression biases in human cortex of genes associated with neurodevelopmental disorders.Semantic proximity Read ↗

Human-specific enrichment of schizophrenia risk-genes in callosal neurons of the developing neocortexSemantic proximity Read ↗

Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants.Semantic proximity Read ↗

Noncanonical Genomic Imprinting Effects in Offspring.Semantic proximity Read ↗

Allele specific expression in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.