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Article

Tuning the primary reaction of channelrhodopsin-2 by imidazole, pH, and site-specific mutations.

Biophysical journal - 6 Jun 2012

Scholz Frank, Bamberg Ernst, Bamann Christian, Wachtveitl Josef

Abstract excerpt

Femtosecond time-resolved absorption measurements were performed to investigate the influence of the pH, imidazole concentration, and point mutations on the isomerization process of Channelrhodopsin-2. Apart from the typical spectral characteristics of retinal isomerization, an additional absorption feature rises for the wild-type (wt) on a timescale from tens of ps to 1 ns within the spectral range of the...

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Identifiers

PMID: 22713581
DOI: 10.1016/j.bpj.2012.04.034
PMCID: PMC3368145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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