Article
The EF loop in green proteorhodopsin affects conformation and photocycle dynamics.
Biophysical journal - 16 Jul 2013
Mehler Michaela, Scholz Frank, Ullrich Sandra J, Mao Jiafei, Braun Markus, Brown Lynda J, Brown Richard C D, Fiedler Sarah A, Becker-Baldus Johanna, Wachtveitl Josef, Glaubitz Clemens
Abstract excerpt
The proteorhodopsin family consists of retinal proteins of marine bacterial origin with optical properties adjusted to their local environments. For green proteorhodopsin, a highly specific mutation in the EF loop, A178R, has been found to cause a surprisingly large redshift of 20 nm despite its distance from the chromophore. Here, we analyze structural and functional consequences of this EF loop mutation by...
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