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Article

Novel MDM2 splice variants identified from oral squamous cell carcinoma.

Oral oncology - 1 Nov 2012

Sam Kin Kit, Gan Chai Phei, Yee Pei San, Chong Chan Eng, Lim Kue Peng, Karen-Ng Lee Peng, Chang Wei Sern, Nathan Sheila, Rahman Zainal Ariff Abdul, Ismail Siti Mazlipah, Cheong Sok Ching

Abstract excerpt

INTRODUCTION: The presence of a variety of MDM2 splice variants has been reported in a range of different tumor types and is associated with poor patient prognosis. Furthermore, several MDM2 variants have been shown to have oncogenic properties. Despite this, MDM2 splice variants have not been comprehensively characterized in oral squamous cell carcinoma (OSCC). MATERIALS AND METHODS: MDM2 splice variants were...

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Share to Carcinoma, Squamous Cell
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Lymphatic Metastasis

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Share to Proto-Oncogene Proteins c-mdm2

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Source

Identifiers

PMID: 22705356
DOI: 10.1016/j.oraloncology.2012.05.016

Genes

MDM2

Provenance

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