Article
Alternative and aberrant splicing of MDM2 mRNA in human cancer.
Cancer cell - 1 Jul 2002
Bartel Frank, Taubert Helge, Harris Linda C
Abstract excerpt
MDM2 has been characterized as a protein that binds to and facilitates degradation of the tumor suppressor p53. Interestingly, more than 40 different splice variants of MDM2 transcripts have been identified both in tumors and normal tissues, and the majority of these variants do not contain seque...
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