Article
VEGF gene polymorphisms and susceptibility to colorectal cancer disease in Italian population.
International journal of colorectal disease - 1 Feb 2009
Maltese Paolo, Canestrari Emanuele, Ruzzo Annamaria, Graziano Francesco, Falcone Alfredo, Loupakis Fotios, Tonini Giuseppe, Santini Daniele, Magnani Mauro
Abstract excerpt
BACKGROUND: The vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in the process of angiogenesis, a crucial phase in tumor growth and metastasis. We carried out a case-control study to evaluate whether polymorphisms of VEGF gene modulate the risk of develo...
Topics
- Aged
- Case-Control Studies
- Colorectal Neoplasms
- Female
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Italy
- Male
- Odds Ratio
- Polymorphism, Single Nucleotide
- Vascular Endothelial Growth Factor A
- White People