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Article

VEGF gene polymorphisms and susceptibility to colorectal cancer disease in Italian population.

International journal of colorectal disease - 1 Feb 2009

Maltese Paolo, Canestrari Emanuele, Ruzzo Annamaria, Graziano Francesco, Falcone Alfredo, Loupakis Fotios, Tonini Giuseppe, Santini Daniele, Magnani Mauro

Abstract excerpt

BACKGROUND: The vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in the process of angiogenesis, a crucial phase in tumor growth and metastasis. We carried out a case-control study to evaluate whether polymorphisms of VEGF gene modulate the risk of developing colorectal cancer disease (CCD). MATERIALS AND METHODS: We evaluated VEGF -2578A/C, -460T/C, and +405C/G genotypes...

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Identifiers

PMID: 18830612
DOI: 10.1007/s00384-008-0586-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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