Article
Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer.
Pharmacogenomics - 1 Dec 2011
Hansen Torben Frøstrup, Jakobsen Anders
Abstract excerpt
Colorectal cancer (CRC) constitutes one of the most common malignancies in the world and, despite advances in diagnostics and treatments, patients still face a poor prognosis and a more individualized treatment approach appears necessary. The VEGF system and angiogenesis are involved in many aspects of tumor biology and the efficacy of chemotherapy, and some targeted therapeutics appear to be related to the...
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