Article
Vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer.
Revista espanola de enfermedades digestivas - 1 Jan 2010
Vidaurreta M, Sánchez-Muñoz R, Veganzones S, Rafael S, Gutiérrez M, de-la-Orden V, Fernández C, Arroyo M, Cerdán F J, Maestro de las Casas Ma Luisa
Abstract excerpt
BACKGROUND: Angiogenesis plays an important role in tumor progression. The vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis. In the present study we evaluated single nucleotide polymorphisms (SNPs) -2578C > A, -1154G > A, and +936C > T in the VEGF gene, and thei...
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Antimetabolites, Antineoplastic
- Chemotherapy, Adjuvant
- Colectomy
- Colonic Neoplasms
- Combined Modality Therapy
- Female
- Fluorouracil
- Genetic Predisposition to Disease
- Genotype
- Humans
- Leucovorin