Article
A polymorphism in the promoter region of the survivin gene is related to hemorrhagic transformation in patients with acute ischemic stroke.
Neuromolecular medicine - 1 Dec 2014
Mallolas Judith, Rodríguez Rocío, Gubern Carme, Camós Susanna, Serena Joaquín, Castellanos Mar
Abstract excerpt
Hemorrhagic transformation (HT) of cerebral infarction is a common and serious occurrence following acute ischemic stroke. The expression of survivin, a member of the inhibitor of apoptosis protein family, has been shown to increase after cerebral ischemia. This protein has been mainly located at the microvasculature within the infarcted and peri-infarcted area, so we aimed to investigate whether survivin gene...
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