Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association study of apoptosis gene polymorphisms in mitochondrial diabetes: A potential role in the pathogenicity of MD.

Gene - 10 Jan 2018

Tabebi Mouna, Khabou Bodour, Boukadi Hanen, Ben Hamad Mariam, Ben Rhouma Bochra, Tounsi Slim, Maalej Abdellatif, Kamoun Hassen, Keskes-Ammar Leila, Abid Mohamed, Mnif Mouna, Fakhfakh Faiza

Abstract excerpt

Mitochondrial diabetes (MD) is a heterogeneous disorder characterized by a chronic hyperglycemia and is maternally transmitted. Syndromic MD is a subgroup of MD including diabetic microangiopathy and macroangiopathy, in addition to extrapancreatic disorder. MD is caused by genetic mutations and deletions affecting mitochondrial DNA. This mitochondrial damage initiates apoptosis. In this study, we hypothesized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochromes c

Share to Diabetes Mellitus

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Mitochondrial Diseases

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 28987347
DOI: 10.1016/j.gene.2017.09.063

Genes

BAK1
BCL2
CASP3
BAX
CASP10
CASP7
CASP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study of apoptosis gene polymorphisms in mitochondrial diabetes: A potential role in the pathogenicity of MD.PMID 28987347Read ↗

Role of mitochondrial DNA in diabetes Mellitus Type I and Type IISemantic proximity Read ↗

The Role of Mitochondrial Mutations and Chronic Inflammation in Diabetes.Semantic proximity Read ↗

Clinical phenotype of mitochondrial diabetes due to rare mitochondrial DNA mutations.Semantic proximity Read ↗

Apoptosis of beta cells in diabetes mellitus.Semantic proximity Read ↗

Apoptosis in the pathophysiology of diabetes mellitus.Semantic proximity Read ↗

Mutations in apoptosis genes: a pathogenetic factor for human disease.Semantic proximity Read ↗

Mitochondrial DNA mutations in diabetic heart.Semantic proximity Read ↗

Mitochondria mediated cell death in diabetesSemantic proximity Read ↗

Impact of single-nucleotide polymorphisms at the TP53-binding and responsive promoter region of BCL2 gene in modulating the phenotypic variability of LGMD2C patients.Semantic proximity Read ↗

Apoptosis in mitochondrial encephalomyopathies with mitochondrial DNA mutations: a potential pathogenic mechanism.Semantic proximity Read ↗

Genetic determinants of neuronal vulnerability to apoptosis.Semantic proximity Read ↗

Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.