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Article

Different inhibitory capacities of human and mouse KLRG1 are linked to distinct disulfide-mediated oligomerizations.

European journal of immunology - 1 Sept 2012

Hofmann Maike, Schweier Oliver, Pircher Hanspeter

Abstract excerpt

The killer cell lectin-like receptor G1 (KLRG1) is a cadherin-binding inhibitory receptor expressed by NK and T cells in humans and mice. Although structural and ligand-binding properties of human (h) and mouse (m) KLRG1 are very similar, KLRG1-mediated inhibition under physiological conditions is only observed with human lymphocytes. Using a well-defined in vitro system, we demonstrate here that mKLRG1 exhibits...

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Source

Identifiers

PMID: 22684915
DOI: 10.1002/eji.201142357

Genes

KLRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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