Article
KLRG1--more than a marker for T cell senescence.
Age (Dordrecht, Netherlands) - 1 Dec 2009
Henson Sian M, Akbar Arne N
Abstract excerpt
The co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1) is expressed on NK cells and antigen-experienced T cells and has been postulated to be a marker of senescence. Whilst KLRG1 has frequently been used as a marker of cellular differentiation, data are emerging indicating that KLRG1 plays an inhibitory role. In this review we examine evidence highlighting this view of KLRG1 with emphasis on the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
