Article
Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors.
Carbohydrate research - 6 Sept 2011
Drozdová Anna, Bojarová Pavla, Křenek Karel, Weignerová Lenka, Henssen Birgit, Elling Lothar, Christensen Helle, Jensen Henrik H, Pelantová Helena, Kuzma Marek, Bezouška Karel, Krupová Monika, Adámek David, Slámová Kristýna, Křen Vladimír
Abstract excerpt
This work reveals new structural relationships in the complex process of the interaction between activation receptors of natural killer cells (rat NKR-P1, human CD69) and novel bivalent carbohydrate glycomimetics. The length, glycosylation pattern and linker structure of receptor ligands were examined with respect to their ability to precipitate the receptor protein from solution, which simulates the in vivo...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
