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Article

Krüppel-like factor 5 protects against murine colitis and activates JAK-STAT signaling in vivo.

PloS one - 1 Jan 2012

Tetreault Marie-Pier, Alrabaa Rami, McGeehan Megan, Katz Jonathan P

Abstract excerpt

Inflammatory bowel disease (IBD), which is characterized by chronic or recurring inflammation of the gastrointestinal tract, affects 1.4 million persons in the United States alone. KLF5, a Krüppel-like factor (KLF) family member, is expressed within the epithelia of the gastrointestinal tract and has been implicated in rapid cell proliferation, migration, and remodeling in a number of tissues. Given these...

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Source

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Identifiers

PMID: 22675454
DOI: 10.1371/journal.pone.0038338
PMCID: PMC3364979

Genes

KLF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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