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Article

A centric view of JAK/STAT5 in intestinal homeostasis, infection, and inflammation

19 Jan 2021

Abstract excerpt

Cytokines, growth factors or hormones take action through the JAK/STAT5 signaling pathway, which plays a critical role in regulating the intestinal response to infection and inflammation. However, the way in which STAT5 regulates intestinal epithelial compartment is largely ignored due to the lack of genetic tools for proper exploration and because the two STAT5 transcription factors (STAT5A and STAT5B) have some...

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PMID: 33482575
DOI: 10.1016/j.cyto.2020.155392

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