Article
Reduced frequency of NKT-like cells in patients with progressive chronic lymphocytic leukemia.
Medical oncology (Northwood, London, England) - 1 Dec 2012
Jadidi-Niaragh Farhad, Jeddi-Tehrani Mahmood, Ansaripour Bita, Razavi Seyed Mohsen, Sharifian Ramazan Ali, Shokri Fazel
Abstract excerpt
Natural killer T (NKT) cells are a subset of innate immune cells displaying a limited repertoire of antigen specificities and CD1d restriction. Little is known about contribution of NKT cells in cancer initiation and progression. In this study, the frequencies of NKT-like cells, B cells expressing CD1d molecule and CD4(+) regulatory (Treg) cells were analyzed in 40 patients with chronic lymphocytic leukemia (CLL)...
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