Dominant cytotoxic NK cell subset within CLPD-NK patients identifies a more aggressive NK cell proliferation

Abstract excerpt

Natural killer (NK) cells represent a class of innate lymphocytes with large granular morphology and cytotoxic functions, characterized by the CD3–/CD16+/CD56+ phenotype. According to CD56 expression, two major NK cell subsets can be recognized, CD56 high /CD16 dim/neg NK cells with the ability to release cytokines and CD56 dim /CD16 high NK cells displaying cytotoxic ability toward virus infected or neoplastic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytomegalovirus and herpesvirus research
• Share to Immune Cell Function and Interaction
• Share to T-cell and B-cell Immunology