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Article

Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease.

Leukemia research - 1 Mar 2011

D'Arena Giovanni, Laurenti Luca, Minervini Maria Marta, Deaglio Silvia, Bonello Lisa, De Martino Laura, De Padua Laura, Savino Lucia, Tarnani Michela, De Feo Vincenzo, Cascavilla Nicola

Abstract excerpt

Regulatory T-cells (Treg) actively maintain immunological self-tolerance and play a significant role in the progression of cancer. Treg cell numbers have been evaluated in 80 patients with previously untreated chronic lymphocytic leukemia (CLL) and in 40 normal healthy volunteers. Treg cells are higher in CLL patients than in controls and correlate with disease status (more advanced clinical stage, peripheral...

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PMID: 20880586
DOI: 10.1016/j.leukres.2010.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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