Article
Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1+ effector memory phenotype.
Cancer immunology, immunotherapy : CII - 1 Nov 2013
Göthert Joachim Rudolf, Eisele Lewin, Klein-Hitpass Ludger, Weber Stefanie, Zesewitz Marie-Louise, Sellmann Ludger, Röth Alexander, Pircher Hanspeter, Dührsen Ulrich, Dürig Jan
Abstract excerpt
Altered numbers and functions of T cells have previously been demonstrated in chronic lymphocytic leukemia (CLL) patients. However, dynamics and specific T-cell subset alterations have not been studied in great detail. Therefore, we studied CLL blood lymphocyte subsets of individual patients in a...
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