Article
Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer.
Oral oncology - 1 Oct 2001
Sreelekha T T, Ramadas K, Pandey M, Thomas G, Nalinakumari K R, Pillai M R
Abstract excerpt
Oral cancer ranks first among all cancers in males and is the third most common among females in India. Tobacco-derived carcinogens are involved in the development of oral cancer. Environment-gene interaction in oral carcinogenesis is well demonstrated by phase I and II enzymes that are involved in the metabolism of carcinogens. This study looked at the significance of genetic polymorphisms in CYP1A1, GSTM1 and...
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