Article
Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer.
Head & neck - 1 Sept 2006
Gattás Gilka Jorge Figaro, de Carvalho Marcos Brasilino, Siraque Maria Salete, Curioni Otávio A, Kohler Priscila, Eluf-Neto Jose, Wünsch-Filho Victor
Abstract excerpt
BACKGROUND: Alcohol intake and tobacco smoke, in addition to other environmental and genetic factors, have been associated with head and neck cancer. We evaluated the role of metabolic enzyme polymorphisms on the risk of head and neck cancer in a hospital-based case-control study. METHODS: CYP1A1MspI, CYP2E1PstI, GSTM1, and GSTT1polymorphisms were evaluated in 103 histologically confirmed head and neck cancer...
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