Article
Genetic variation in carcinogen metabolizing genes associated with oral cancer in pakistani population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Masood Nosheen, Kayani Mahmood Akhtar, Malik Fraz Arshad, Mahjabeen Ishrat, Baig Ruqia Mehmood, Faryal Rani
Abstract excerpt
BACKGROUND: Xenobiotics are metabolized by either phase I enzymes like CYP1A1 or phase II enzymes like GSTs. Polymorphisms in the encoding genes (CYP1A1, GSTM1, GSTT1 and GSTP1) potentially may therefore contribute towards risk association for oral cancer. METHODOLOGY: These genes were investigated via a case control study consisting of 228 oral cancer patients and 150 cancer free normal individuals as controls....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
