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Article

Frequent occurrence of mitochondrial DNA mutations in Barrett's metaplasia without the presence of dysplasia.

PloS one - 1 Jan 2012

Lee Soong, Han Moon-Jong, Lee Ki-Sang, Back Seung-Chul, Hwang David, Kim Hwan-Young, Shin Jong-Hee, Suh Soon-Pal, Ryang Dong-Wook, Kim Hye-Ran, Shin Myung-Geun

Abstract excerpt

BACKGROUND: Barrett's esophagus (BE) is one of the most common premalignant lesions and can progress to esophageal adenocarcinoma (EA). The numerous molecular events may play a role in the neoplastic transformation of Barrett's mucosa such as the change of DNA ploidy, p53 mutation and alteration of adhesion molecules. However, the molecular mechanism of the progression of BE to EA remains unclear and most studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22629421
DOI: 10.1371/journal.pone.0037571
PMCID: PMC3358277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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