Article
Identification of abnormal nuclear and mitochondrial genes in esophageal cancer cells.
Molecular medicine reports - 1 Feb 2018
Liu Zongwen, Chai Ting, Zhang Yan, Chu Alan, Liang Bing, Guo Xing, Guo Zhenjiang, Song Rui, Hou Ge, Yuan Jinjin, Liu Yaohe, Zhang Yuhao
Abstract excerpt
The present study aimed to detect the mutation characteristics of mitochondrial DNA (mtDNA) in Eca109 of Ec9706 cells, and to investigate their association with the nuclear genome (nDNA), thus providing a basis for gene targeting therapies for esophageal squamous cell carcinoma (ESCC). In vitro‑cultured Ec9706 and Eca109 cells were analyzed the changes of single‑nucleotide polymorphisms (SNPs),...
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