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Article

A TRP5/5-fluoroanthranilic acid counter-selection system for gene disruption in Candida guilliermondii.

Current genetics - 1 Aug 2012

Foureau Emilien, Clastre Marc, Millerioux Yoann, Simkin Andrew J, Cornet Lucie, Dutilleul Christelle, Besseau Sébastien, Marais Emeline, Melin Céline, Guillard Jérôme, Crèche Joël, Giglioli-Guivarc'h Nathalie, Courdavault Vincent, Papon Nicolas

Abstract excerpt

Candida guilliermondii is an interesting biotechnological model for the industrial production of value-added metabolites and also remains an opportunistic emerging fungal agent of candidiasis often associated with oncology patients. The aim of the present study was to establish a convenient transformation system for C. guilliermondii by developing both an ATCC 6260-derived recipient strain and a recyclable...

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PMID: 22618436
DOI: 10.1007/s00294-012-0377-3

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